Key Benefits

• Supports normal homocysteine metabolism with betaine, B6, B12, and folate.
• Helps reduce tiredness and fatigue thanks to folate, B6, and B12.
• Contributes to normal psychological and immune function.
• Provides active, tissue-ready nutrients for effective absorption.

Feel energised and supported every day. Thorne’s Methyl-Guard blends betaine, 5-MTHF folate, methyl-B12, and P5P (active B6) to help your body’s natural methylation process. These nutrients work together to support normal homocysteine metabolism, energy-yielding metabolism, and the healthy function of your immune and nervous systems.

With active forms of B vitamins, Methyl-Guard is designed for easy absorption and gentle support. Folate, B6, and B12 contribute to the reduction of tiredness and fatigue, while also playing a role in normal psychological function and red blood cell formation. It’s a simple way to help maintain your wellbeing, every day.

Methyl-Guard addresses a critical biochemical process—methylation—that impacts everything from cardiovascular health to cognitive function and bone strength. Unlike standard supplements, Methyl-Guard provides nutrients in their active, tissue-ready forms, ensuring superior absorption and effectiveness. This is especially important for those who have a genetic mutation that impairs methylation. By supporting healthy homocysteine levels and offering comprehensive benefits across multiple systems, Methyl-Guard provides a more targeted, effective, and holistic approach to maintaining overall wellbeing.

Thorne sets the standard for excellence in the supplement industry. Recommended by over 100 professional sports teams and U.S. National Teams, Thorne offers a curated bundle of clean, science-backed supplements and treats designed to fuel your body naturally and effectively. With more than 30 years of dedication to quality, Thorne's commitment to purity and potency begins with sustainably sourced ingredients and rigorous testing. Every supplement undergoes four rounds of testing to ensure optimal absorption, safety, and efficacy, making Thorne the trusted choice for both health-conscious individuals and professionals.

With our Healf Curation Process, we do the work for you. Shop with confidence knowing that every item has been tried, tested, and curated for you.

Learn more about each step—Brand Discovery, Expert Validation, and Community Testing—here.

Betaine Anhydrous (Trimethylglycine), Folate (L-5-MTHF), Vitamin B12 (Methylcobalamin), Vitamin B6 (Pyridoxal 5'-Phosphate). Other Ingredients: Calcium (Citrate), Calcium Laurate, Hypromellose Capsule, Silicon Dioxide.

Take three capsules twice daily or as recommended by your healthcare professional.

Additional Information:

Food supplements and foods sold by Healf should not be used as a substitute for a varied, balanced diet and healthy lifestyle.

If you are pregnant, breastfeeding, have a medical condition, or are taking any medications, please consult with a healthcare professional before use. Use products only if the seal is intact. Store in a cool, dry place, out of the reach of young children. Do not exceed the recommended daily intake.

We make every effort to ensure that product information on our website is accurate and up to date, but packaging and ingredients may occasionally vary from images shown on site. Please refer to the product label and contact Healf before use if you have any questions regarding your specific allergies or intolerances.